Prof. Harish Hirani,
Director, CSIR-CMERI |
The Motivation
Oxygen
Supplies have been marring the entire National Landscape since the advent of
the COVID-19 Second Wave in March 2021. One of the major projected obstacles
for the seamless flow of Oxygen across the Healthcare Facilities is the associated
heavily complicated Oxygen Transportation Logistics i.e. Specialized Cryogenic
Tanks, which besides being not available off-the-shelf also requires intensive
Capital inputs. Besides, people were also forced to buy spurious Oxygen
Concentrators lacking Reliability and Trustworthiness in terms of durability,
endurance and performance.
In
this scenario, it was felt that there is a need for Science & Technology to
pitch-in and evolve Socio-Techno-Economic Model which primarily tries to
achieve the following goals:
- Decentralized
Generation of Oxygen which is sans the Capital-intensive and Complicated Oxygen
Delivery Logistics. The Decentralized Oxygen Generation model also ensures that
there is a more democratic and widespread network of Oxygen Generation hubs
across the Nation.
-
The
in-situ Oxygen Generation Model would help in Localized Enriching of Oxygen and
thus involve and engage the local communities in concentrating and managing
this invaluable Medical Intervention resource.
- Involving
a Wider Community Participation in the Implementation Strategy- That pools
together the Innovators, Business Entities, Healthcare Professionals, Financial
Institutions and the Community.
- Engaging the MSMEs for the development of a robust Economic Model and better outreach to the targeted areas. Besides, the motive was also to empower the MSMEs through interactive Virtual Sessions with proper Technical Training, comprehensive Exchange of Knowledge and Learning interactions.
The Technology
Figure 1 |
Technology for Optimised Dosage of Oxygen through Advanced Technologies- A veritable answer to the Oxygen Short Supply
In addition, as per Scientific Reports our Inhalation process
consumes only 1/3rd time of a Single Respiratory Cycle and the rest
2/3rd time is consumed for the process of exhalation. However, as a
regular practice Oxygen is continuously administered to a patient. Thus, it can
be logically concluded that almost 30-40% of the Oxygen is wasted in the
process. This process of wastage can be appropriately controlled through
appropriate technology interventions such as Advanced Pulse Dosage mechanism,
which will be based upon timely dosage of Oxygen and will be sensed through
appropriate Respiratory sensors. We are happy to inform that CSIR-CMERI is
working upon the development of this Technology.
Advanced
Oxygen Administering Systems
As per available Medical Journals, the usage of Nasal Cannula
without Masks leads to significant transmission of Viral Load to nearby
attendants. Even covered Oxygen Masks might lead to leakage of Viral Load
through the small perforations on the sides of the masks, though in a much
reduced level. Thus wearing N95 masks on top of the Nasal Cannula might contain
this leakage to a certain extent; however, N95 masks might hinder the normal
breathing process.
In this context, we are focused upon the development of Oxygen Delivery using appropriate NIV Masks/Hoods which would have separate inhaling and exhaling channels. The exhaling channel would be equipped with an efficient Viral/Bacterial Filter for trapping any transmission. (Fig 2&3)This would be extremely helpful in enclosed spaces such as Isolation Wards. The Oxygen dosage would be based upon the Respiratory sensors to ensure appropriate quantities of Oxygen is delivered as per need. The exhaled air would also be analyzed for Oxygen and the same would be reutilized for Oxygen generation, which would be again reused.
Figure 2 | Figure 3 |
With the onset of the COVID first and second wave, it has been observed that the larger Medical Establishments has bearing most of the load for COVID treatment. This situation has led to larger Medical Establishments being over-burdened.
There is a need of developing Oxygen Enrichment Capacity of 100 LPM which can supply Oxygen for 10-bedded facilities (Up to 10 LPM for each bed). This is possible owing to the fact that the Compressor Unit and the Concentration Units are separate. Thus, this enables the entire system to function with a Single Compressor. The Oxygen Enrichment Unit would be located on the bedside and the FiO2 control would be optional. (Fig. 4.)
Figure 4 |
Existing Hospital Infrastructure
There was a huge ramping up of the Oxygen Plants during the
recent COVID surges. Many Medical Establishments either boosted or setup Oxygen
Plants in their facilities which may not be affordable for Small or Rural
Hospitals. Thus, another Concept is also being worked upon whereby the Hybrid
Version of the Advanced Oxygen Enrichment Technology will have the added
advantage of being able to function along with Hospital Oxygen/Oxygen Cylinders
for Intelligent Switching and Interventions in a variable manner. This
technology will help in complementing Oxygen shortfalls, when the situation so
arises.
Partnering
with MSMEs for an Inclusive Business Model
Figure 5 |
Figure 6 |
What will be the Business Prospects of the Technology Post-COVID?
To address the future viability of manufacturing Oxygen Products, it was informed the MSMEs that Oxygen Therapy will be relevant even in the days to come, since it is used as a Non-Invasive Therapy for faster Wound Healing, Cell Repair and self-healing of organs. The technology also has tremendous potential for applications in the domains of high-altitude defense as well as in places with high-altitude having significant tourist footfalls where it can be used as Oxygen Rejuvenation Hubs for fatigued tourists. The Anti-Microbial properties of Oxygen have significant regenerative capabilities and thus numerous other Medical applications. This multitude of application in diverse fields implies that the CSIR-CMERI developed Oxygen Enrichment Technology will remain Economically Viable as a business prospect for the MSMEs.
Future Strategy
Further R&D in this direction has led to explore possibilities of improving the versatility of the product through applications in numerous scenarios. A need was steadily felt for further improvising the technology through value-additions, which would expand its usability and multiply its effectiveness. The Advanced Oxygen Enrichment Unit is being developed having Independent Controls for Oxygen Enrichment (FiO2) and Flow Rate. It can be equipped with SPO2 sensor and C-PAP with an estimated capacity of 15 LPM of enriched Oxygenated Air (93+3%). The Prototype experiments have been showing encouraging results and might soon see the light of the day.
List of Business Associations and Institutes CSIR-CMERI partnered with for Awareness Generation of the Business Entities (Fig. 7a-7c):
- MSME-Development Institute, Raipur- 25.04.2021
- MSME-Development Institute, Ahmedabad-29.04.2021
- MSME-Development Institute, Cuttack-30.04.2021
- MSME-Development Institute,
Indore-30.04.2021
- MSME-Development Institute,
Varanasi-03.05.2021
- MSME-Development Institute,
Jaipur- 04.05.2021
- MSME-Development Institute,
Karnal, Haryana-05.05.2021
- MSME-Development Institute,
Ranchi-07.05.2021
- MSME-Development Institute,
Thrissur-11.05.2021
- MSME-Development Institute,
Durgapur-14.05.2021
- MSME-Development Institute,
Ahmedabad-24.05.2021
- MSME-Development Institute,
Ranchi-25.05.2021
- MSME-Development Institute,
Mumbai & Aurangabad-27.05.2021
- MSME-Development Institute,
Indore-31.05.2021
- MSME-Development Institute,
Jammu & Kashmir-04.06.2021
Professional Organizations (Fig.
7):
- PHD Chamber of Commerce & Industry, New Delhi- 18.05.2021
- ASSOCHAM, East and North East-19.05.2021
- Indian Medical Association, Tamil Nadu-29.05.2021
- FICCI Kerala State Council-01.06.2021
- SIDBI, Assam- 02.06.2021
Figure 7a |
Figure 7b |
Figure 7c |
The massive MSME Outreach and Awareness Exercise conducted by CSIR-CMERI have resulted in 13 MSMEs across the Nation being handed the Know-How of this indigenously developed Technology. Out of these 13 MSMEs few have already developed Prototype and it has been rolled out to the markets.
The CSIR-CMERI Oxygen Enrichment Technology has received tremendous response from both the MSMEs and the Media Houses across the Nation. Some of the media coverage by prominent Media houses are mentioned (Fig. 8):
Figure 8 |
- https://pib.gov.in/PressReleseDetailm.aspx?PRID=1707470
- https://pib.gov.in/PressReleasePage.aspx?PRID=1710350
- https://www.outlookindia.com/newsscroll/oxygen-enrichment-device-for-use-in-homes-remote-locations-developed-by-cmeri/2061097?utm_source=amp&utm_medium=wa&utm_campaign=amp
- https://youtu.be/CYVYyY6LYQ8 (Times Now)
- https://pib.gov.in/PressReleasePage.aspx?PRID=1713400
- https://economictimes.indiatimes.com/news/india/covid-19-csir-lab-develops-technology-to-meet-oxygen-demand-minimise-storage-risks/articleshow/82201412.cms
- http://www.uniindia.com/csir-cmeri-develops-oxygen-enrichment-unit-an-optimised-oxygen-administration-device-to-combat-nationwide-oxygen-supply-shortage/east/news/2377321.html#.YIF60QJufCg.whatsapp
- https://www.financialexpress.com/lifestyle/science/covid-19-csir-lab-develops-technology-to-meet-oxygen-demand-minimise-storage-risks/2238462/
- https://www.thehindubusinessline.com/news/csir-cmeri-transfers-oxygen-enrichment-unit-tech-to-hyderabad-company/article34390212.ece
- https://youtu.be/CWG4txh6BLk (DD India)
- https://pib.gov.in/PressReleasePage.aspx?PRID=1714106
- https://pib.gov.in/PressReleasePage.aspx?PRID=1714854
- https://pib.gov.in/PressReleasePage.aspx?PRID=1714976
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1714854
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1714919
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1715035
- https://pib.gov.in/PressReleasePage.aspx?PRID=1715371
- https://pib.gov.in/PressReleasePage.aspx?PRID=1715379
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1715883
- https://pib.gov.in/PressReleasePage.aspx?PRID=1715979
- https://pib.gov.in/PressReleasePage.aspx?PRID=1716408
- https://bartamanpatrika.com/home?cid=14&id=293294
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1716983
- https://pib.gov.in/PressReleasePage.aspx?PRID=1717785
- https://pib.gov.in/PressReleasePage.aspx?PRID=1718239
- https://pib.gov.in/PressReleasePage.aspx?PRID=1718589
- https://pib.gov.in/PressReleasePage.aspx?PRID=1720740
- https://www.financialexpress.com/industry/sme/more-msmes-get-cmeris-technology-to-ramp-up-production-of-oeu-devices-generating-medical-oxygen/2257325/
- https://pib.gov.in/PressReleasePage.aspx?PRID=1722250
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1722436
- https://pib.gov.in/PressReleasePage.aspx?PRID=1722743
- https://pib.gov.in/PressReleasePage.aspx?PRID=1723435
- https://pib.gov.in/PressReleasePage.aspx?PRID=1723632
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1723749
- https://www.pib.gov.in/PressReleseDetail.aspx?PRID=1724455
- http://www.uniindia.com/jammu-kashmir-now-shows-interest-about-wb-csir-cmeri-oeu-technology/east/news/2413084.html#.YLo4WDgmQ40.whatsapp
- https://pib.gov.in/PressReleasePage.aspx?PRID=1724770
- https://pib.gov.in/PressReleasePage.aspx?PRID=1724758
- http://ddnews.gov.in/sci-tech/csir-cmeri-come-out-quick-solutions-deal-oxygen-shortage
- https://economictimes.indiatimes.com/news/science/oxygen-enrichment-device-for-use-in-homes-remote-locations-developed-by-cmeri/articleshow/81968793.cms?from=mdr
- https://www.expresshealthcare.in/news/csir-cmeri-developed-o2-enrichment-technology-may-be-effective-to-treat-covid-19-patients/428251/
- https://www.abpeducation.com/news/csir-cmeri-develops-oxygen-enrichment-unit/cid/1208952
- https://knnindia.co.in/news/newsdetails/msme/csir-cmeri-empowering-msmes-for-an-oxygen-sufficient-india
- https://indianewsrepublic.com/o2-enrichment-technology-developed-by-csir-cmeri-may-be-effective-in-treating-patients-with-covid-19/286249/
- https://www.theweekendleader.com/Headlines/60481/csircmeri-develops-oxygen-enrichment-tech-for-treating-covid-patients.html
- http://vigyanprasar.gov.in/isw/Good-news-amidst-the-nationwide-oxygen-shortage.html
- https://timesofindia.indiatimes.com/india/covid-19-csir-institutions-come-out-with-quick-solutions-to-deal-with-oxygen-shortage/articleshow/82087899.cms
- https://www.jagran.com/west-bengal/bardhaman-oxygen-enrichment-unit-21665100.html
- https://www.bhaskarhindi.com/city/news/jk-msmes-upgrade-their-understanding-of-csir-cmeri-advanced-oxygen-technologies-255949
- https://insamachar.com/csir-cmeri-msme-development-institute-indore-medical-association-of-india-and-laghu-udyog-bharati-agree-to-empower-msmes-for-an-oxygen-rich-india/
- https://dhyeyaias.in/current-affairs/daily-current-affairs/csir-cmeri-oxygen-enrichment-unit
https://www.cmeri.res.in/technology/oxygen-enrichment-unit
Dr. Anjali Chatterjee
Head, Department of Business, Innovation and Skills
CSIR-CMERI, Durgapur
e-mail: bdg@cmeri.res.in
Phone: 9434720494